Messina to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Messina Centrale and arrive at Caltanissetta Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Messina to Caltanissetta train schedule: the first train leaves at 05:00, while the last ride is at 16:20. A Messina to Caltanissetta train cost about 11.0 €. But how long is the train ride from Messina to Caltanissetta? Your journey takes about 4 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Messina to Caltanissetta and find low cost tickets starting from 11 €!