Messina to Mazara del Vallo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Messina Centrale and arrive at Mazara del Vallo every about 6 hours on average. If travelling with Trenitalia, you need to know the Messina to Mazara del Vallo train schedule: the first train leaves at 07:08, while the last ride is at 14:23. A Messina to Mazara del Vallo train cost about 16.8 €. But how long is the train ride from Messina to Mazara del Vallo? Your journey takes about 7 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Messina to Mazara del Vallo and find low cost tickets starting from 18 €!