Messina to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Messina Centrale and arrive at Niscemi every about 4 hours on average. If travelling with Trenitalia, you need to know the Messina to Niscemi train schedule: the first train leaves at 12:18, while the last ride is at 16:35. A Messina to Niscemi train cost about 11.0 €. But how long is the train ride from Messina to Niscemi? Your journey takes about 5 hours on average.