To get from Messina to Palermo by train you can catch one of the 8 trains that everyday travel between these two cities. The first train to Palermo leaves from Messina at 06:45 and the last train departs at 19:55. If you choose a local train the trip lasts on average 02:42 hours. For your trip from Messina to Palermo by train you can choose to leave from one of Messina main stations: Messina Centrale Tickets price depend on the departure time and train type, the most economic train ticket available this week is from € 12 to € 25. The most economic train is Regionale () that departs at 11:25 and arrives in Palermo at 15:00 at € 12. On Wanderio you can compare all schedules, fares and railway companies to Palermo and book the best itinerary starting from Messina.