Messina to Palermo trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 8 daily rides to get from Messina to Palermo. If travelling with Trenitalia, you need to know the Messina to Palermo train schedule: the first train leaves at 06:45, while the last ride is at 19:10. A Messina to Palermo train cost about 11.8 €. But how long is the train ride from Messina to Palermo? Your journey takes about 3 hours on average. Trenitalia offers 6 direct trains between these two cities. Thanks to Trenitalia offers, you can save on your trip from Messina to Palermo and find prices starting from 12 €! If you need to travel this week, prices range from 25.50 € to 25.50€.