Messina to Pozzuoli trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Reggio di Calabria Centrale, Villa S. Giovanni and arrive at Napoli Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Messina to Pozzuoli train schedule: the first train leaves at 14:00, while the last ride is at 21:55. A Messina to Pozzuoli train cost about 19.92 €. But how long is the train ride from Messina to Pozzuoli? Your journey takes about 5 hours on average. Trenitalia offers 4 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Messina to Pozzuoli and find low cost tickets starting from 12 €!