Messina to Trapani trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Messina Centrale and arrive at Trapani every about 4 hours on average. If travelling with Trenitalia, you need to know the Messina to Trapani train schedule: the first train leaves at 07:08, while the last ride is at 14:23. A Messina to Trapani train cost about 19.1 €. But how long is the train ride from Messina to Trapani? Your journey takes about 7 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Messina to Trapani and find low cost tickets starting from 20 €!