Messina to Treviglio trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Messina Centrale and arrive at Treviglio every about 2 hours on average. If travelling with Trenitalia, you need to know the Messina to Treviglio train schedule: the first train leaves at 00:35, while the last ride is at 16:40. A Messina to Treviglio train cost about 111.9 €. But how long is the train ride from Messina to Treviglio? Your journey takes about 16 hours on average.