Mestre to Pozzallo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Venezia Mestre and arrive at Pozzallo every about 4 hours on average. If travelling with Trenitalia, you need to know the Mestre to Pozzallo train schedule: the first train leaves at 00:21, while the last ride is at 18:37. A Mestre to Pozzallo train cost about 127.65 €. But how long is the train ride from Mestre to Pozzallo? Your journey takes about 18 hours on average.