Mestre to Siderno trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Venezia Mestre and arrive at Siderno every about 2 hours on average. If travelling with Trenitalia, you need to know the Mestre to Siderno train schedule: the first train leaves at 00:21, while the last ride is at 19:54. A Mestre to Siderno train cost about 88.95 €. But how long is the train ride from Mestre to Siderno? Your journey takes about 18 hours on average.