Mestre to Trieste trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Venezia Mestre and arrive at Trieste Centrale every 30 minutes on average. If travelling with Trenitalia, you need to know the Mestre to Trieste train schedule: the first train leaves at 05:10, while the last ride is at 22:53. A Mestre to Trieste train cost about 13.00 €. But how long is the train ride from Mestre to Trieste? Your journey takes about 2 hours on average. Trenitalia offers 27 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Mestre to Trieste and find low cost tickets starting from 9 €! If you need to travel this week, prices range from 13.00 € to 19.90€. Booking your train ticket a few weeks in advance though, you can find low cost trains from Mestre to Trieste with fares starting from 9.90€, saving 35% on average.