Mestre to Varese trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Venezia Mestre and arrive at Milano Porta Garibaldi every about 2 hours on average. If travelling with Trenitalia, you need to know the Mestre to Varese train schedule: the first train leaves at 10:37, while the last ride is at 18:37. A Mestre to Varese train cost about 68.0 €. But how long is the train ride from Mestre to Varese? Your journey takes about 3 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Mestre to Varese and find low cost tickets starting from 21 €!