Mestre to Ventimiglia trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Venezia Mestre and arrive at Ventimiglia every about 2 hours on average. If travelling with Trenitalia, you need to know the Mestre to Ventimiglia train schedule: the first train leaves at 10:02, while the last ride is at 17:32. A Mestre to Ventimiglia train cost about 56.5 €. But how long is the train ride from Mestre to Ventimiglia? Your journey takes about 8 hours on average.