Milan to Noto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Milano Porta Venezia and arrive at Noto every about 12 hours on average. If travelling with Trenitalia, you need to know the Milan to Noto train schedule: the first train leaves at 19:39, while the last ride is at 19:39. A Milan to Noto train cost about 121.85 €. But how long is the train ride from Milan to Noto? Your journey takes about 21 hours on average.