Milan to Rome trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed , since many high speed Trenitalia trains are available on this route , as well as Intercity, InterCityNotte, Trenitalia trains . You can count on 14 daily rides to get from Milan to Rome. Trains leave from Milano Centrale and arrive at Roma Tiburtina every 60 minutes on average. If travelling with Trenitalia, you need to know the Milan to Rome train schedule: the first train leaves at 10:15, while the last ride is at 20:50. A Milan to Rome train cost about 55 €. But how long is the train ride from Milan to Rome? Your journey takes about 4 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Milan to Rome and find low cost tickets starting from 7 €! If you need to travel this week, prices start from 38€ to a maximum price of 67€. When booking your train ticket a few weeks in advance though, you can find low cost trains from Milan to Rome with fares starting from 22€, saving up to 41%.