Milan to Rome trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 39 daily rides to get from Milan to Rome. Trains leave from Milano Centrale and arrive at Roma Termini every 20 minutes on average. The trip by train from Milan to Rome last on average 02:55 travelling with high-speed trains (Frecciarossa or Italotreno) If travelling with Trenitalia, you need to know the Milan to Rome train schedule: the first train leaves at 05:42, while the last ride is at 22:15. A Milan to Rome train cost about 34.90 €. But how long is the train ride from Milan to Rome? Your journey takes about 4 hours on average. Trenitalia offers 36 direct trains between these two cities. Thanks to Trenitalia offers, you can save on your trip from Milan to Rome and find prices starting from 19 €! If you need to travel this week, prices range from 39.90 € to 69.90€. Booking your train ticket a few weeks in advance though, you can find low cost trains from Milan to Rome with fares starting from 34.90€, saving 51% on average.