Milazzo to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Milazzo and arrive at Niscemi every about 2 hours on average. If travelling with Trenitalia, you need to know the Milazzo to Niscemi train schedule: the first train leaves at 11:06, while the last ride is at 22:36. A Milazzo to Niscemi train cost about 12.5 €. But how long is the train ride from Milazzo to Niscemi? Your journey takes about 7 hours on average.