Milazzo to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Milazzo and arrive at Palermo Centrale every 60 minutes on average. If travelling with Trenitalia, you need to know the Milazzo to Palermo train schedule: the first train leaves at 05:21, while the last ride is at 19:34. A Milazzo to Palermo train cost about 10.4 €. But how long is the train ride from Milazzo to Palermo? Your journey takes about 3 hours on average. Trenitalia offers 12 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Milazzo to Palermo and find low cost tickets starting from 9 €! If you need to travel this week, prices start from 20.50€.