Misterbianco to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Catania Centrale and arrive at Siracusa every about 4 hours on average. If travelling with Trenitalia, you need to know the Misterbianco to Syracuse train schedule: the first train leaves at 18:44, while the last ride is at 18:44. Trenitalia offers 1 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Misterbianco to Syracuse and find low cost tickets starting from 6 €! If you need to travel this week, prices range from 10.50 € to 10.50€.