Molfetta to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Molfetta and arrive at Castelvetrano every about 2 hours on average. If travelling with Trenitalia, you need to know the Molfetta to Castelvetrano train schedule: the first train leaves at 06:54, while the last ride is at 23:27. A Molfetta to Castelvetrano train cost about 72.35 €. But how long is the train ride from Molfetta to Castelvetrano? Your journey takes about 10 hours on average.