Molfetta to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Molfetta and arrive at Niscemi every about 3 hours on average. If travelling with Trenitalia, you need to know the Molfetta to Niscemi train schedule: the first train leaves at 18:11, while the last ride is at 23:27. A Molfetta to Niscemi train cost about 75.85 €. But how long is the train ride from Molfetta to Niscemi? Your journey takes about 23 hours on average.