Molfetta to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Molfetta and arrive at Siracusa every about 3 hours on average. If travelling with Trenitalia, you need to know the Molfetta to Syracuse train schedule: the first train leaves at 06:31, while the last ride is at 22:31. A Molfetta to Syracuse train cost about 71.2 €. But how long is the train ride from Molfetta to Syracuse? Your journey takes about 17 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Molfetta to Syracuse and find low cost tickets starting from 80 €!