Mondragone to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Falciano-Mondragone-Carinola and arrive at Messina Centrale every about 3 hours on average. If travelling with Trenitalia, you need to know the Mondragone to Messina train schedule: the first train leaves at 07:30, while the last ride is at 22:43. A Mondragone to Messina train cost about 51.6 €. But how long is the train ride from Mondragone to Messina? Your journey takes about 7 hours on average.