Monopoli to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Monopoli and arrive at Caltanissetta Centrale every about 12 hours on average. If travelling with Trenitalia, you need to know the Monopoli to Caltanissetta train schedule: the first train leaves at 21:54, while the last ride is at 21:54. A Monopoli to Caltanissetta train cost about 62.1 €. But how long is the train ride from Monopoli to Caltanissetta? Your journey takes about 23 hours on average.