Monopoli to Comiso trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Monopoli to Comiso. Trains leave from Monopoli and arrive at Comiso every about 12 hours on average. If travelling with Trenitalia, you need to know the Monopoli to Comiso train schedule: the first train leaves at 21:54, while the last ride is at 21:54. A Monopoli to Comiso train cost about 65.35 €. But how long is the train ride from Monopoli to Comiso? Your journey takes about 1 hour on average.