Monopoli to Niscemi trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Monopoli to Niscemi. Trains leave from Monopoli and arrive at Niscemi every about 12 hours on average. If travelling with Trenitalia, you need to know the Monopoli to Niscemi train schedule: the first train leaves at 21:54, while the last ride is at 21:54. A Monopoli to Niscemi train cost about 61.75 €. But how long is the train ride from Monopoli to Niscemi? Your journey takes about 24 hours on average.