Monopoli to Palermo trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 2 daily rides to get from Monopoli to Palermo. The first train to Palermo leaves from Monopoli at 04:41 and the last train departs at 23:40. If you choose a local train the trip lasts on average 18:19 hours. For your trip from Monopoli to Palermo by train you can choose to leave from one of Monopoli main stations: Monopoli On Wanderio you can compare all schedules, fares and railway companies to Palermo and book the best itinerary starting from Monopoli.