Monopoli to Syracuse trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Monopoli to Syracuse. Trains leave from Monopoli and arrive at Siracusa every about 12 hours on average. If travelling with Trenitalia, you need to know the Monopoli to Syracuse train schedule: the first train leaves at 06:38, while the last ride is at 06:38. A Monopoli to Syracuse train cost about 64.2 €. But how long is the train ride from Monopoli to Syracuse? Your journey takes about 16 hours on average.