Naples to Milan trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Napoli Centrale and arrive at Milano Centrale every 60 minutes on average. If travelling with Trenitalia, you need to know the Naples to Milan train schedule: the first train leaves at 13:00, while the last ride is at 22:07. A Naples to Milan train cost about 39.90 €. But how long is the train ride from Naples to Milan? Your journey takes about 6 hours on average. Trenitalia offers 13 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Naples to Milan and find low cost tickets starting from 24 €! When booking your train ticket a few weeks in advance though, you can find low cost trains from Naples to Milan with fares starting from 24.90€, saving up to 56%.