Niscemi to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Niscemi and arrive at Alpignano every about 6 hours on average. If travelling with Trenitalia, you need to know the Niscemi to Alpignano train schedule: the first train leaves at 06:22, while the last ride is at 18:08. A Niscemi to Alpignano train cost about 183.4 €. But how long is the train ride from Niscemi to Alpignano? Your journey takes about 12 hours on average.