Niscemi to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Niscemi and arrive at Palermo Notarbartolo every about 6 hours on average. If travelling with Trenitalia, you need to know the Niscemi to Palermo train schedule: the first train leaves at 06:22, while the last ride is at 06:22. A Niscemi to Palermo train cost about 16.1 €. But how long is the train ride from Niscemi to Palermo? Your journey takes about 9 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Niscemi to Palermo and find low cost tickets starting from 14 €!