Niscemi to Trieste trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Niscemi and arrive at Trieste Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Niscemi to Trieste train schedule: the first train leaves at 06:22, while the last ride is at 18:08. A Niscemi to Trieste train cost about 127.8 €. But how long is the train ride from Niscemi to Trieste? Your journey takes about 6 hours on average.