Nola to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Nola and arrive at Messina Centrale every about 6 hours on average. If travelling with Trenitalia, you need to know the Nola to Messina train schedule: the first train leaves at 09:38, while the last ride is at 12:47. A Nola to Messina train cost about 46.2 €. But how long is the train ride from Nola to Messina? Your journey takes about 6 hours on average.