Noto to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Noto and arrive at Alessandria every about 3 hours on average. If travelling with Trenitalia, you need to know the Noto to Alessandria train schedule: the first train leaves at 09:26, while the last ride is at 20:38. A Noto to Alessandria train cost about 125.45 €. But how long is the train ride from Noto to Alessandria? Your journey takes about 20 hours on average.