Novara to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Novara and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Novara to Messina train schedule: the first train leaves at 07:05, while the last ride is at 22:38. A Novara to Messina train cost about 111.5 €. But how long is the train ride from Novara to Messina? Your journey takes about 17 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Novara to Messina and find low cost tickets starting from 36 €!