Novate Milanese to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Milano Certosa, Salerno and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Novate Milanese to Messina train schedule: the first train leaves at 22:01, while the last ride is at 22:01. If you need to travel this week, prices start from 45.50€. When booking your train ticket a few weeks in advance though, you can find low cost trains from Novate Milanese to Messina with fares starting from 9.90€, saving up to 56%.