Novi Ligure to Caltagirone trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Novi Ligure and arrive at Caltagirone every about 3 hours on average. If travelling with Trenitalia, you need to know the Novi Ligure to Caltagirone train schedule: the first train leaves at 11:44, while the last ride is at 22:44. A Novi Ligure to Caltagirone train cost about 122.1 €. But how long is the train ride from Novi Ligure to Caltagirone? Your journey takes about 9 hours on average.