Novi Ligure to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Novi Ligure and arrive at Enna every about 12 hours on average. If travelling with Trenitalia, you need to know the Novi Ligure to Enna train schedule: the first train leaves at 15:16, while the last ride is at 15:16. A Novi Ligure to Enna train cost about 234.45 €. But how long is the train ride from Novi Ligure to Enna? Your journey takes about 20 hours on average.