Orta Nova to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Ortanova and arrive at Comiso every about 12 hours on average. If travelling with Trenitalia, you need to know the Orta Nova to Comiso train schedule: the first train leaves at 16:36, while the last ride is at 16:36. A Orta Nova to Comiso train cost about 124.7 €. But how long is the train ride from Orta Nova to Comiso? Your journey takes about 20 hours on average.