Osimo to Ragusa trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Osimo-Castelfidardo and arrive at Ragusa every about 6 hours on average. If travelling with Trenitalia, you need to know the Osimo to Ragusa train schedule: the first train leaves at 13:51, while the last ride is at 13:55. A Osimo to Ragusa train cost about 136.25 €. But how long is the train ride from Osimo to Ragusa? Your journey takes about 22 hours on average.