Osimo to Varese trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Ancona, Osimo-Castelfidardo and arrive at Milano Porta Garibaldi, Milano Centrale, Varese, Firenze S. M. Novella every 10 minutes on average. If travelling with Trenitalia, you need to know the Osimo to Varese train schedule: the first train leaves at 02:31, while the last ride is at 22:24. A Osimo to Varese train cost about 20.6 €. But how long is the train ride from Osimo to Varese? Your journey takes about 5 hours on average. Trenitalia offers 9 direct trains between these two cities.