Ostuni to Manfredonia trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Ostuni and arrive at Manfredonia every about 4 hours on average. If travelling with Trenitalia, you need to know the Ostuni to Manfredonia train schedule: the first train leaves at 14:06, while the last ride is at 16:59. A Ostuni to Manfredonia train cost about 16.8 €. But how long is the train ride from Ostuni to Manfredonia? Your journey takes about 3 hours on average.