Padua to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Padova and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Padua to Syracuse train schedule: the first train leaves at 00:45, while the last ride is at 17:18. A Padua to Syracuse train cost about 113.5 €. But how long is the train ride from Padua to Syracuse? Your journey takes about 20 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Padua to Syracuse and find low cost tickets starting from 77 €!