Palermo to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Palermo Centrale and arrive at Alpignano every about 3 hours on average. If travelling with Trenitalia, you need to know the Palermo to Alpignano train schedule: the first train leaves at 12:54, while the last ride is at 21:10. A Palermo to Alpignano train cost about 121.5 €. But how long is the train ride from Palermo to Alpignano? Your journey takes about 20 hours on average.