Palermo to Anzio trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Palermo Centrale and arrive at Villa Claudia every about 2 hours on average. If travelling with Trenitalia, you need to know the Palermo to Anzio train schedule: the first train leaves at 18:30, while the last ride is at 21:10. A Palermo to Anzio train cost about 62.6 €. But how long is the train ride from Palermo to Anzio? Your journey takes about 14 hours on average.