Palermo to Anzio trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Palermo Centrale and arrive at Villa Claudia every about 2 hours on average. If travelling with Trenitalia, you need to know the Palermo to Anzio train schedule: the first train leaves at 18:30, while the last ride is at 21:10. A Palermo to Anzio train cost about 62.6 €. But how long is the train ride from Palermo to Anzio? Your journey takes about 14 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Palermo to Anzio and find low cost tickets starting from 33 €!