Palermo to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Palermo Notarbartolo and arrive at Caltanissetta Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Palermo to Caltanissetta train schedule: the first train leaves at 07:12, while the last ride is at 19:12. A Palermo to Caltanissetta train cost about 8.3 €. But how long is the train ride from Palermo to Caltanissetta? Your journey takes about 2 hours on average.