Palermo to Marsala trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Palermo Notarbartolo and arrive at Mozia-Birgi every about 2 hours on average. If travelling with Trenitalia, you need to know the Palermo to Marsala train schedule: the first train leaves at 06:52, while the last ride is at 18:24. A Palermo to Marsala train cost about 8.3 €. But how long is the train ride from Palermo to Marsala? Your journey takes about 4 hours on average. Trenitalia offers 2 direct trains between these two cities.