Palermo to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Palermo Notarbartolo and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Palermo to Syracuse train schedule: the first train leaves at 07:14, while the last ride is at 15:44. A Palermo to Syracuse train cost about 14.5 €. But how long is the train ride from Palermo to Syracuse? Your journey takes about 7 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Palermo to Syracuse and find low cost tickets starting from 15 €!