Palermo to Trieste trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Palermo Notarbartolo and arrive at Trieste Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Palermo to Trieste train schedule: the first train leaves at 09:10, while the last ride is at 20:44. A Palermo to Trieste train cost about 116.25 €. But how long is the train ride from Palermo to Trieste? Your journey takes about 16 hours on average.