Palermo to Varese trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Palermo Centrale and arrive at Varese every about 2 hours on average. If travelling with Trenitalia, you need to know the Palermo to Varese train schedule: the first train leaves at 12:54, while the last ride is at 21:10. A Palermo to Varese train cost about 119.7 €. But how long is the train ride from Palermo to Varese? Your journey takes about 21 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Palermo to Varese and find low cost tickets starting from 46 €!