Palermo to Venice trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Palermo Centrale and arrive at Venezia S. Lucia every about 2 hours on average. If travelling with Trenitalia, you need to know the Palermo to Venice train schedule: the first train leaves at 12:57, while the last ride is at 21:10. A Palermo to Venice train cost about 128.0 €. But how long is the train ride from Palermo to Venice? Your journey takes about 15 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Palermo to Venice and find low cost tickets starting from 74 €!