Perugia to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Perugia and arrive at Caltanissetta Centrale every about 12 hours on average. If travelling with Trenitalia, you need to know the Perugia to Caltanissetta train schedule: the first train leaves at 17:56, while the last ride is at 17:56. A Perugia to Caltanissetta train cost about 99.4 €. But how long is the train ride from Perugia to Caltanissetta? Your journey takes about 18 hours on average.